(CNN) -- This much was certain Tuesday: former paramilitary leader and crime boss suspect Daniel Alejandro Serna was no longer under house arrest in Medellin, Colombia. Other than that, there was a lot of head-scratching and finger-pointing.

Did the four men dressed as prison guards who took Serna away Sunday night help him escape or did they abduct him because he might be squealing to authorities?

Who was responsible for making sure he did not leave his home? Prison officials say it wasn't their job and they tried to warn against house arrest. Prosecutors say it wasn't their job either, and they asked the national police to keep a tight eye on Serna. All sides blame the others.

Perhaps the best summation of the whole mess came from Medellin Mayor Alonso Salazar. "I don't know what the judges or the prosecutors think or who gave the authority, but there's something that doesn't smell right to me in all of this," Salazar told Caracol Radio.

Meanwhile, the mystery continued Tuesday: Is the prisoner who goes by the nickname of Kener a free man or a dead man? A $264,000 reward for information leading to his capture might help provide an answer.

The case has even drawn the attention of President Alvaro Uribe, who said Monday he is worried about decisions by judicial officials to allow house arrests and prisoner transfers that make it easier for dangerous high-level criminals to escape.

"All the aforementioned creates a lack of confidence in the ability by institutions to overcome impunity and gravely affects the tasks by the armed forces and citizens' confidence," Uribe said.

Those comments, he said, were aimed respectfully toward Attorney General Guillermo Mendoza Diago and the president of the Supreme Court, Elsy del Pilar Cuello Calderon.

Serna was arrested in July 2008. Authorities say he was one of the bosses for the armed branch of Colombia's narcotrafficking cartels and was involved with former drug lords Daniel "Don Mario" Rendon Herrera and Diego "Don Berna" Murillo Bejarano.

He is being tried in Medellin on aggravated homicide and conspiracy charges and has another 13 pending cases throughout the nation.

A few weeks ago, a local prosecutor allowed Serna to be placed under house arrest for medical reasons. He is said to suffer variously from kidney disease, high blood pressure and intestinal problems.

Authorities made him wear an ankle bracelet monitoring device but records indicate he violated his house arrest twice before leaving for good, Caracol Radio reported.

He left his home at 10 p.m. on February 18 and returned not quite four hours later. On March 1, the radio station said, Serna left at 6:52 p.m. and returned at 7:13 p.m.

Sunday night's absence was more open-ended, especially after he removed the ankle bracelet.

Officials say four men wearing guard uniforms drove up to his house in southern Medellin and said they were transferring Serna to a prison. He was listed as missing at midnight.

By Monday, the blame game was on full display.

Carlos Barragan, director of Colombia's national prison authority, known as Inpec, said he sounded the alarm about the perils of house arrest for Serna.

"We warned prosecutors about the dangers of this person and the intelligence information that we had from other authorities that it was possible that he would carry out an escape," Barragan said.

Furthermore, he said, prison officials are not responsible because there are no guidelines for such incarceration in his department.

Attorney General Mendoza said prison officials are indeed responsible for anyone under house arrest.

Miguel Ceballos, vice minister for the federal Justice Department, shifted blame to the national police. Justice Department officials had asked the national police to form a security ring around the house, Ceballos said.

He also said prison officials should be held accountable if they were at fault.

"If the Inpec is responsible," Ceballos said, "let's determine it and put the responsible party in jail."

Interior Minister Fabio Valencia Cossio said Tuesday there were no police reinforcements at Serna's home because prosecutors did not ask for additional security.

Furthermore, he said, ankle bracelets are designed to be used only on non-dangerous criminals.

Medellin prosecutors said they were just following procedures for a medically verified sick prisoner.

"It is a legal decision because in all instances we are talking about a grave illness, with enough supporting evidence," said Martha Penagos, head of prosecutors in Medellin.

While officials try to determine who was responsible, they say they're also on the hunt for Serna.