CHICAGO, Illinois (CNN) -- President-elect Barack Obama said "a very affectionate thanks" to the people of Illinois in a letter published Sunday in the Chicago Sun-Times and other newspapers across his home state.
Barack Obama walks to his vehicle after a workout at a gym in Chicago on Saturday.
Obama announced on Thursday that his resignation from the U.S. Senate is official as of Sunday.
"Today, I am ending one journey to begin another," Obama's letter said. "After serving the people of Illinois in the United States Senate -- one of the highest honors and privileges of my life -- I am stepping down as senator to prepare for the responsibilities I will assume as our nation's next president."
Obama wrote about moving to Illinois two decades ago "as a young man eager to do my part in building a better America."
"On the South Side of Chicago, I worked with families who had lost jobs and lost hope when the local steel plant closed. It wasn't easy, but we slowly rebuilt those neighborhoods one block at a time, and in the process I received the best education I ever had," he wrote.
Obama followed his years as a community organizer and lawyer with a successful bid for the Illinois state Senate.
"It was in Springfield, in the heartland of America, where I saw all that is America converge -- farmers and teachers, businessmen and laborers, all of them with a story to tell, all of them seeking a seat at the table, all of them clamoring to be heard. It was there that I learned to disagree without being disagreeable; to seek compromise while holding fast to those principles that can never be compromised, and to always assume the best in people instead of the worst," his letter said.
"I still remember the young woman in East St. Louis who had the grades, the drive and the will but not the money to go to college. I remember the young men and women I met at VFW halls across the state who serve our nation bravely in Iraq and Afghanistan. And I will never forget the workers in Galesburg who faced the closing of a plant they had given their lives to, who wondered how they would provide health care to their sick children with no job and little savings," he wrote.
Obama said his memories of the people of Illinois "will stay with me when I go to the White House in January."
"The challenges we face as a nation are now more numerous and difficult than when I first arrived in Chicago, but I have no doubt that we can meet them. For throughout my years in Illinois, I have heard hope as often as I have heard heartache. Where I have seen struggle, I have seen great strength. And in a state as broad and diverse in background and belief as any in our nation, I have found a spirit of unity and purpose that can steer us through the most troubled waters," he wrote.
"To this place, and the kindness of these people, I owe everything," he quoted Lincoln as writing about Illinois.
"Today, I feel the same, and like Lincoln, I ask for your support, your prayers, and for us to 'confidently hope that all will yet be well,'" Obama wrote.
His letter concluded:
"With your help, along with the service and sacrifice of Americans across the nation who are hungry for change and ready to bring it about, I have faith that all will in fact be well. And it is with that faith, and the high hopes I have for the enduring power of the American idea, that I offer the people of my beloved home a very affectionate thanks."
Obama's Senate office will close sometime within two months. His Senate staff will spend that time coordinating with his replacement, advising constituents with open requests, and archiving documents for Obama's presidential library.
Several Illinois Democrats, including Rep. Jesse Jackson Jr. and Iraq war veteran Tammy Duckworth, a former congressional candidate who now serves in Gov. Rod Blagojevich's administration, have been mentioned as possible Senate replacements for Obama.
Blagojevich, a Democrat who will appoint Obama's successor, announced last week that he was assembling a panel to look over likely candidates.
Obama's replacement would be up for re-election in 2010.
Vice president-elect Joe Biden, who was also re-elected in Delaware to his Senate seat on November 4, told an interviewer several weeks ago that he would resign when he's sworn in as vice president in January.