Sebelius spokeswoman Nicole Corcoran said the governor was there to celebrate the 59th birthday of her husband, Gary.
But Chicago also is where President-elect Barack Obama's transition team is headquartered.
Even before the election, Sebelius had been mentioned as a potential Cabinet appointee, and she's surfaced as a potential Energy or Health and Human Services secretary.
Corcoran said the Chicago trip was planned well in advance of the election and that Sebelius didn't meet with Obama or members of his transition team.
She and her husband flew to Chicago on Friday and returned to Kansas on Sunday.
(Copyright 2008 by The Associated Press. All Rights Reserved.)