(CNN) -- Paul Newman's handsome face and solid acting made him a popular and respected film star.
1 of 3 more photos » He died Friday, according to spokeswoman Marni Tomljanovic.
Newman attained stardom in the 1950s and never lost the movie-star aura, appearing in such classic films as "Cat on a Hot Tin Roof," "Exodus," "The Hustler," "Cool Hand Luke," "Butch Cassidy and the Sundance Kid," "The Sting" and "The Verdict."
He finally won an Oscar in 1986 -- on his eighth try -- for "The Color of Money," a sequel to "The Hustler." He later received two more Oscar nominations. Among his other awards was the Motion Picture Academy's Jean Hersholt Humanitarian Award.
"Paul took advantage of what life offered him, and while personally reluctant to acknowledge that he was doing anything special, he forever changed the lives of many with his generosity, humor, and humanness," said Robert Forrester, vice chairman of the actor's Newman's Own Foundation. "His legacy lives on in the charities he supported and the Hole in the Wall Camps, for which he cared so much."
He was often willing to make fun of himself. Early in his career he was mistaken for fellow Method actor Marlon Brando; Newman obligingly signed autographs, "Best wishes, Marlon Brando." Read more reaction to from Paul Newman's friends and family »
Watch a special edition of "Larry King Live" remembering the late Paul Newman.
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Newman was a Method-trained actor who blazed his own career trail and didn't shy away from risky roles -- inside and outside films. Watch a look back at Newman's career »
A portrayal as a race-car driver in 1969's "Winning" led to his actual competition in races; at 70, he participated in the 24 Hours of Daytona and he was still racing at age 80.
He stumped for liberal causes, including Eugene McCarthy's 1968 presidential candidacy, and earned a spot on Richard Nixon's enemies list -- "the highest single honor I've ever received," he said.
In 1982, Newman and his friend A.E. Hotchner founded Newman's Own, a food company that produced food ranging from pasta sauces to salad dressing to chocolate chip cookies.
"The embarrassing thing is that the salad dressing is outgrossing my films," Newman once wryly noted.
To date, the company -- which donates all profits to charities such as Newman's Hole in the Wall camps -- has given away more than $200 million. Newman established the camp to benefit gravely ill children.
"He saw the camps as places where kids could escape the fear, pain and isolation of their conditions, kick back and raise a little hell," Forrester said.
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Today, there are 11 Hole in the Wall camps around the world, with additional programs in Africa and Vietnam. Some 135,000 children have attended the camps -- free of charge.
The Association of Hole in the Wall Camps "is part of his living legacy, and for that we remain forever grateful," the association said in a statement.
"We are greatly saddened by his passing. His leadership and spirit can never be replaced. But he has left us strong and confident."
Newman was half of one of the most successful showbiz marriages -- to Joanne Woodward, whom he married in 1958. He observed that just because he was a sex symbol there was no reason to commit adultery.
"Why would I go out for a hamburger when [I] have steak at home?" he asked.
Newman's daughters said described him as a devoted husband, a loving father, an adoring grandfather and a dedicated philanthropist.
"Our father was a rare symbol of selfless humility, the last to acknowledge what he was doing was special," they said in a statement. "Intensely private, he quietly succeeded beyond measure in impacting the lives of so many with his generosity.
"Always and to the end, Dad was incredibly grateful for his good fortune. In his own words: 'It's been a privilege to be here.'"
The statement requested privacy for Newman's family.
CNN's Larry King, who interviewed Newman through the years, said he greatly admired the actor.
"He lived a long and terrific life," King said Saturday morning. "He was much appreciated. Did some theater, graduated Yale. Long marriage to Joanne Woodward. One of those showbiz rarities." Watch Larry King reminisce about Paul Newman »
Paul Leonard Newman was born on January 26, 1925, in Shaker Heights, Ohio, a suburb of Cleveland. His father owned a successful sporting goods store, but young Paul was taken with his mother's and uncle's interest in the arts and started acting while still in grade school.
"I wasn't running toward the theater but running away from the sporting goods store," he said later.
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After being kicked out of Ohio University for unruly behavior, he joined the Navy and served for three years during World War II. After the war he attended Kenyon College in Gambier, Ohio, where his unruly ways led him to theater.
Newman continued studying acting at Yale and at New York's Actors' Studio, earning jobs in the growing medium of television.
He made his Broadway debut in William Inge's 1953 play "Picnic," opposite Kim Stanley, one of the most successful stage actresses of her time. The next year he made his first Hollywood film, "The Silver Chalice," a bomb that he mocked for the rest of his life. He even took out a newspaper ad apologizing for his performance.
But success as boxer Rocky Graziano in "Somebody Up There Likes Me" (1956) made him a star, and more hits followed: "The Long, Hot Summer" (1958) opposite his soon-to-be wife, Woodward; "Cat on a Hot Tin Roof" (1958) with Elizabeth Taylor; and "The Young Philadelphians" (1959).
But the 1960s were to be Newman's decade, a perfect match for his ironic, anti-establishment attitude. iReport.com: What do you remember best about Paul Newman?
He began the decade with "Exodus" (1960), an epic about Israel's founding directed by Otto Preminger, and succeeded it with "The Hustler" (1961) as pool shark Fast Eddie Felson; "Sweet Bird of Youth" (1962), another Tennessee Williams work; and "Hud" (1963), "Harper" (1966) and "Hombre" (1967), continuing a good-luck streak of films beginning with "H."
After "Cool Hand Luke" (1967), in which he played the egg-eating malcontented title character, he turned to directing, earning raves for his behind-the-camera work on "Rachel, Rachel" (1968), starring his wife. Watch Newman discuss what he would have done differently »
"Butch Cassidy and the Sundance Kid" (1969) and "The Sting" (1973) teamed Newman with co-star Robert Redford and director George Roy Hill. The trio proved to be box-office gold: They were two of the highest-grossing films of their time, winning a slew of awards -- including a best picture Oscar for the latter, a tale of con men in 1930s Chicago.
Newman finally teamed up with Steve McQueen, who had been scheduled to be his co-star in "Butch Cassidy," in 1974's "The Towering Inferno." Though the Irwin Allen-produced disaster film earned mixed critical notices, it, too, was one of the most successful box-office films of the era. Watch how Newman worked his magic »
Newman's career started faltering in the late '70s as he turned his attention to his other pursuits, notably racing. The loss of his son Scott to a drug overdose in 1978 hit the actor hard.
He made an artistic comeback with 1982's "The Verdict," the story of an ambulance-chasing hard-luck lawyer in which Newman appeared broken, raspy and every inch of his 57 years.
By the time Newman starred in "The Color of Money," directed by Martin Scorsese, his movie career had slipped a notch. Never afraid of playing his age, Newman portrayed a repressed businessman in 1990's "Mr. and Mrs. Bridge," a cantankerous lodger in "Nobody's Fool" (1994), a fatherly, retired gangster in "Road to Perdition" (2002), and the voice of a Hudson Hornet in "Cars" (2006).
He gained some of his best reviews for his performance as the stage manager in a Broadway production of Thornton Wilder's classic play, "Our Town," filmed for television in 2003, and was perfectly cast as the rascally father to Ed Harris' responsible diner owner in the miniseries "Empire Falls."
In recent years, Newman talked about doing another film with his friend Redford, but the two couldn't settle on a script. In 2007, Newman said he was retiring from acting, saying he'd lost confidence in his abilities. Still, he marveled at his own resilience.
"You can't be as old as I am without waking up with a surprised look on your face every morning: 'Holy Christ, whaddya know - I'm still around!' It's absolutely amazing that I survived all the booze and smoking and the cars and the career."
Newman, who was married to Jackie Witt from 1949 to 1957, is survived by his wife, Joanne Woodward, and five children.